4 Dissipation half-life provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. REACH registration dossiers notifications. Precautionary measures and guidance on safe use concern the use and handling of the specific substance, not of the presence of the substance in other articles or mixtures. This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Data is generally standardised and displayed in milligram per litre/cubic metre. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. This section summarises the values related to the screening tests for biodegradation in water from all registered dossiers for the substance. 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As the critical effect is local, succinic acid is assigned to Peak Limitation Category I. Sed elementum odio augue, eget iaculis lorem faucibus vel. Data is generally displayed in milligram per kilo bodyweight. level’ as the dose descriptor. More information about the EC Inventory can be found here. The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications. Succinic acid: Description: Succinic acid is a dicarboxylic acid. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. At concentration of 1 mM, it has a pH of 3.65. The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory. Data is generally displayed in milligrams per kilogram bodyweight per day. Succinic Acid is Strongly Acidic. Its pKa at 25°C are 4.21 and 5.64 . Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. Half-life in water provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C. Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual). Information in the ‘Scientific properties’ section is structured by substance properties, further broken down into endpoints. 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ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Contents. By summarising this information in a single page, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Registrants can report substance information on viscosity as: Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C. This section displays the values related to genetic toxicity from all registered dossiers for the substance. See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’. Values are generally displayed in milligram per kilo food. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment,  generally displayed in milligrams per kilogram (dry weight). With the spirits of "sincere and faithful, guaranteed quality, top-ranking service, consumer paramountcy", we have established good business relations with many large enterprises and makes friends from all over the world. This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance. It is soluble in water and slightly soluble in ethanol for the preparation of pentaheterocyclic compounds.Specification:Test ItemsSp In eukaryotes, succiniate, the anion of succinic acid, is an intermediate in the citric acid cycle, being formed from succinyl CoA and being converted to fumarate. This section summarises the density values from all registered dossiers for the substance. 8 Identification Name Succinic acid Accession Number DB00139 Description. Harmonised classifications (√ - check mark). If not, check our Amber Healing Properties post, to learn more about amber and the way it influences human body. This site is not fully supported in Internet Explorer 7 (and earlier versions). Other release to the environment of this substance is likely to occur from: indoor use (e.g. RST is the consecutive number of the substance in the series ABC. The information has not been reviewed or verified by ECHA or any other authority. Trade names gives all public trade names submitted to ECHA in REACH registrations. This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance. Maintaining Succinic acid is a diprotic acid. If the substance is classified under more than one CLH entry (e.g. This means that at pH 3.50, most succinic acid (83.9%) is present in its undissociated form; monodissociated succinate ion accounts only for approximately 16%, while the dissociation of the second carboxylic group is practically negligible (Usseglio-Tomasset, 1985). Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. More detailed information is available in the dossiers. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. This section summarises the pH values from all registered dossiers for the substance. This section summarises the water solubility values from all registered dossiers for the substance. Skin sensitisation provides substance information on the substance’s sensitisation effect on the skin. For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. 4 The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. If so, the data provided is not processed for the Brief Profile. Annex XVII (Restriction list) – indicates if the substance is included in the list of restrictions. These production facilities could make their process more value-added by using their waste carbon dioxide and biomass, such as cane molasses and cheese whey for succinic acid production. 100 mM 10 mM 1 mM. Also known as: butanedioic acid. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header . Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Applicant’s summary and conclusion – Interpretation of results provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options: Note: Registrants can also select ‘other’ as picklist option for describing the biodegradation values of the substance in water. The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. EC10 / LC10 or NOEC for freshwater fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. O. Data is generally standardised and the displayed in milligram per litre or molar per litre. Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. This section provides information on the derived no- or minimal effect level (DN(M)EL), the level of exposure above which a human should not be exposed to a substance. If more than one value is available, results are displayed as concatenated distinct values, ordered from most to least commonly provided, with the percentage of provided values appended. Praesent et nulla orci. Please see the registered dossiers for substance information for the following endpoints: The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. More than two weeks should pass before a second course is given. Long-term EC10 or LC10 or NOEC for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the terrestrial plants in the test, or the no observed effect concentration for terrestrial plants. It was primarily used externally for rheumatic aches and pains. LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre. The R&D costs associated with petro-based succinic acid, in terms of labor, and ra… If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method). Data is generally displayed in milligrams per litre. This information has not been reviewed or verified by ECHA, and may change without prior notice. Dissociating Properties provides substance information by picklist values: Dissociation Constant provides numerical substance information on the substance’s dissociation constant values at a temperature measured in °C. This section summarises the surface tension values from all registered dossiers for the substance. Fusce eget lorem sed purus tempus blandit. The pKa values for succinic acid, pKa1 = 4.61 and pKa2 = 5.61, lie below the optimal growth and production pH of many organisms. the minimum numerical value associated with the highest priority picklist item. Active substance approval – indicates if the substance is an approved biocidal active substance. C&L Inventory . Registrants can choose from the following picklist endpoint conclusions/effect levels: This section displays the values related to sensitisation from all registered dossiers for the substance. Readily biodegradable but failing the 10-day window. Note: Results without a concentration value are not processed for the Brief Profile. The structure is a computer generated visualisation of the molecular structure derived from the InChI character string. The PIC regulatory processes identified for the Brief Profile are: The ’About this substance’ section provides an overview of the volume in which this substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Otherwise data is displayed reported as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…). Data is generally standardised and displayed in milligram per litre or molar per litre. To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier. EC Inventory, REACH pre-registration, Other, FCM and Articles Regulation, Annex I - Authorised Substances, EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, FCM and Articles Regulation, Annex I - Authorised Substances. 3 . Otherwise data is displayed reported as provided by the registrant(s). Buffer pKa and pH Range Values For preparation of . Our products are Pigments Series, Succinic Acid and Succinic Acid series, (Disodium Succinate, Dikalium succinate, Calcium Succinate, Diethyl Succinate, Diemethyl Succinate), Fine Anhydrous Calcium Chloride, etc., 90% of which are exported to U.S.A., Britain and other twenty countries and regions in the world. Notification – indicates that notified C&L’s have been submitted to ECHA for a substance. Each InChI string starts with the InChI version number followed by the main layer. These substances cannot be placed on the market or used after a given date, unless an authorisation is granted for their specific use, or the use is exempted from authorisation. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C. If so, the data provided is not processed in the Brief Profile. Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Displayed is the most conservative of the prioritised value(s). Within the context of REACH, impurities are unintended constituents present in a substance as manufactured. 3 Data is generally displayed in milligrams per kilogram sediment (dry weight) or in milligram per litre. The % is based on count of values provided. 1 000 g will be displayed as 1 kg. Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. The identification of applicable legislative frameworks is done automatically and without manual verification. The BPR addresses the placing on the market and use of biocidal products, which are used to protect humans, animals, materials or articles against harmful organisms, like pests or bacteria, by regulating the active substances contained in a biocidal product. Succinic acid pKas: 4.20 and 5.60. 5 This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance. Information on the most sensitive study can be provided by the registrants as: Dermal exposure provides information on the substance’s hazard assessment conclusions regarding dermal exposure (for workers). Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. example@lookchem.com, Please enter your password with 6 - 20 characters, Your message must be between 20-2000 letters. This section summarises the values related to phototransformation in water from all registered dossiers for the substance. Registrants can identify the origin of their substance as being: If more than one type of substance is registered, both types will be displayed. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’. Hazard for predators provides information on the substance’s hazard assessment conclusion related to predators/secondary poisoning. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. Values are generally displayed in milligrams per kilogram (dry weight). EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. Pre-registration allows companies to continue manufacturing and importing their. Solubility in organic solvents / fat solubility. This substance is used in the following products: pH regulators and water treatment products, anti-freeze products, metal surface treatment products, heat transfer fluids, hydraulic fluids and washing & cleaning products. level’ as the dose descriptor. Values are generally displayed in milligram per kilo soil (dry weight). Biodegradation in water provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options: This section summarises the values related to the simulation tests for biodegradation in water and sediments from all registered dossiers for the substance. Regulatory process names gives the names under which the substance appears in ECHA's regulatory processes and lists. No summary exists for this scientific endpoint. Malonic Acid pKas: 2.85 and 5.70. 2 The pKa level and structure of succinic acid are similar to those of tartaric acid, which, like succinic acid, is a solid. This substance is used in the following areas: printing and recorded media reproduction, health services and scientific research and development. The quality and correctness of the information remains the responsibility of the data submitter. In analogy to phosphoric acid … Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. El ácido succínico (IUPAC, ácido butanodioico) es un ácido dicarboxílico de fórmula C4H6O4. The Agency thus cannot guarantee the correctness of the information displayed. 1.3), Very insensitive substances with mass explosion hazard (Div. The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. Half-life in air provides substance information on the substance’s dissipation half-life in air in seconds/minutes/hours/days/weeks/months/years. Succinic acid (butanedioic acid) is a dicarboxylic acid that occurs naturally in plant and animal tissues. EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram sediment (dry weight). Su nombre proviene del latín succinum, que quiere decir ámbar, de donde puede extraerse. If multiple values are available, the most conservative value (the highest percentage) is displayed. Oxalic Acid – C. 2. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. Precautions for using this substance have been recommended by its registrants under REACH, as follows: When handling this substance: wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier. Results without measurement conditions (pressure) are not processed for the Brief Profile. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. The basis of SMILES is the representation of a valence model of a molecule. Registrants can register their substance’s bioaccumulation properties as: Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. Jin An industry park, Chizhou economic technical development zone, Anhui, Escrow ServiceMoreSecure Your Orders With escrow More Transparency,Less Uncertainty. If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). Study records behind the presented results and – if applicable - data waving.! Occurs in nature in such organisms as fungi and lichens our Amber Healing properties post, to more. 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